城西大学薬学部紀要

ISSN 1348-4931
24号
2004年1月

♦ STM observation of thia[11]hetero helicene on gold(111) and gold(110) surface ・・・・・・・・・・・・・・・・・・・・ Taniguchi Masahiro / Nakagawa Hiroko / Yamagishi Akihiko / Yamada Kohichi (1)
♦ 113Sn-113mIn generator with a glass beads colum ・・・・・・・・・・・・・・・・・・・・ Teranishi Kunie / Yamaashi Yasuko / Maruyama Yoshiaki (2)
♦ Antioxidative Activty of Allium victarialis L. Extracts ・・・・・・・・・・・・・・・・・・・・ Shirataki Yoshiaki / Matohashi Noboru / Tani Satoru / Sunaga Katsuyoshi / Sakagami Hiroshi / Satoh Kazue /Nakashima Hideki / Kanamoto Taisei / Wolfard Kristina / Molnar Joseph (3)
♦ Effects of Prenylflavanones from Sophora Species on Growth and Activation of Mouse Macrophage-like Cell line ・・・・・・・・・・・・・・・・・・・・ Tashiro Miyuki / Suzuki Fumika / Shirataki Yoshiaki / Yokote Yoshiko / Akahane Kiso / Matohashi Noboru / Ishihara Mariko / Jiang Yi / Sakagami Hiroshi (4)
♦ Stilbene Derivatives from Two Species of Gnetaceae ・・・・・・・・・・・・・・・・・・・・ Iliya Ibrahim / Tanaka Toshiyuki / Iinuma Munekazu / Ali Zulfiqur / Furusawa Miyuki / Nakaya Ken-ichi / Shirataki Yoshiaki / Murata Jin / Darnaed Dedy (5)
♦ Inhibitory Effects of Echinoisoflavanone and Sophoraisoflavanone D in Sophora chrysophylla Seem. on Copper Ion-Induced protein Oxidative Modification of Mouse Brain Homogenate In Vitro ・・・・・・・・・・・・・・・・・・・・ Toda Shizuo / Shirataki Yoshiaki (6)
♦ Lipid Membrane Perturbation Caused by Some Isoflavones and Phenothiazines, and The Activity of These Compounds as Inhibitors of Multidrug Resistance ・・・・・・・・・・・・・・・・・・・・ Michalak Krystyna / Hendrich Andrzej B. / Wesolowska Olga / Pola Andrzej / Lania-Pietrzak Barbara / Motohashi Noboru / Shirataki Yoshiaki / Molnarr Joseph (7)
♦ Stilbene Oligomers in Roots of Sophora moorcroftiana ・・・・・・・・・・・・・・・・・・・・ Shirataki Yoshiaki / Tanaka Toshiyuki / Ohyama Masayoshi / Toda Shizuo / Iinuma Munekazu (8)
♦ Cancer prevention and therapy with kiwifruit in Chinese folklore medicine: a study of kiwifruit extracts ・・・・・・・・・・・・・・・・・・・・ Motohashi Noboru / Shirataki Yoshiaki / Kawase Masami /Tani Satoru / Sakagaami Hiroshi / Satoh Kazue / Kurihara Teruo / Nakashima Hideki / Mucsi Ilona / Varga Andreas / Molnar Joseph (9)
♦ Differential interaction of Sophora isoflavonoids with lipid bilayers ・・・・・・・・・・・・・・・・・・・・ Hendrich Andrzej B. / Malon Rafal / Pola Andrzej / Shirataki Yoshiaki / Motohashi Noboru / Michalak Krystyna (10)
♦ Effects of Isoflavones from Sophora Species on the Growth and Activation of a Mouse Macrophage-like Cell Line ・・・・・・・・・・・・・・・・・・・・ Tashiro Miyuki / Suzuki Fumika / Shirataki Yoshiaki / Yokote Yoshiko / Akahane Kiso / Motohashi Noboru / Ishihara Mariko / Satoh Kazue / Sakagami Hiroshi (11)
♦ Inhibitory Effects of Isoflavones in Sophora moorcroftiana on Lipid Peroxidation by Superoxide ・・・・・・・・・・・・・・・・・・・・ Toda Shizuo / Shirataki Yoshiaki (12)
♦ Reactivity of 2-Methylene-1,3-dicarbonyl Compounds. 1,3-Dipolar Cycloaddition Reaction with Nitrile Oxide. ・・・・・・・・・・・・・・・・・・・・ Yamauchi Masashige (13)
♦ The Influence of Ligand Side Chain on the Enantioselectivity of Lewis Acid Catalyzed Diels-Alder Reactions ・・・・・・・・・・・・・・・・・・・・ Yamauchi Masashige / Itai Kazuhiro / Honda Yuko (14)
♦ New Method for the Synthesis of Nitriles from O-Arylaldoximes with ZrCl4 ・・・・・・・・・・・・・・・・・・・・ Tsuji Chiho / Miyazawa Etsuko / Sakamoto Takeshi / Kikugawa Yasuo (15)
♦ Introduction of a Hydroxy Group at the Para Position and N-Iodophenylation of N-Arylamides Using Phenyliodine(III) Bis(trifluoroacetate) ・・・・・・・・・・・・・・・・・・・・ Itoh Naoki / Sakamoto Takeshi / Miyazawa Etsuko / Kikugawa Yasuo (16)
♦ 3,5-Dibenzoyl-1,4-dihydropyridines: Synthesis and MDR Reversal in Tumor Cells ・・・・・・・・・・・・・・・・・・・・ Kawase Masami / Shah Anamik / Gaveriya Harsukh / Motohashi Noboru / Sakagami Hiroshi / Varga Andreas / Molnar Joseph (17)
♦ Interaction between 3,4-dihydropyridines and ampicillin, and erythromycin on different E. coli strains ・・・・・・・・・・・・・・・・・・・・ Gunics Gyorgyi / Farkas Sandor / Motohashi Noboru / Shah Anamik / Harsukh Gaveriya / Kawase Masami / Molnar Joseph (18)
♦ Partial purification of cytotoxic substances from Moxa extract ・・・・・・・・・・・・・・・・・・・・ Hatsukari Ikusuke / Hitosugi Naoko / Ohno Rie / Nakamura Shinichi / Mizukami Satoshi / Nagasaka Hiroshi / Matsumoto Isao / Kikuchi Hirotaka / Nishikawa Hirofumi / Niitsu Masaru / Kawase Masami / Negoro Takaharu / Satoh Kazue / Nakashima Hideki / Sakagami Hiroshi (19)
♦ Interaction between various resistance modifiers and apoptosis inducer 12H-Benzo[a]phenothiazine ・・・・・・・・・・・・・・・・・・・・ Mucsi Ilona / Varga Andreas / Kawase Masami / Motohashi Noboru / Molnar Joseph (20)
♦ Preparations of heterospirostanols and their pharmacological activities ・・・・・・・・・・・・・・・・・・・・ Quan Hanh-Ji / Koyanagi Jyunichi / Ohmori Koichi / Uesato Shinichi / Tsuchido Tetsuaki / Saito Setsuo (21)
♦ Mass Spectrometric Separation and Determination of N1,N12-Diacetylspermine in the Urine of Cancer Patients ・・・・・・・・・・・・・・・・・・・・ Kobayashi Masaki / Samejima Keijiro / Hiramatsu Kyoko / Kawakita Masao (22)
♦ Simultaneous Determination of Endogenous and Orally Administered 15N-Labeled Polyamines in Rat Organs ・・・・・・・・・・・・・・・・・・・・ Xu Yong Ji / Hara Takeshi / Samejima Keijiro / Sasaki Hitomi / Niitsu Masaru (23)
♦ IF3, a novel cell-differentiation factor, highly expressed in murine liver and ovary. ・・・・・・・・・・・・・・・・・・・・ Mano Hiroshi / Sachie Nakatani / Aoyagi Rika / Ishii Rina / Iwai Yuka / Shimoda Nanako / Jincho Yuko / Hiura Hitoshi / Hirose Minako / Mochizuki Chikako / Yuri Motoko/ Im Ryang Hyock / Funada-Wada Ulala / Wada Masahiro (24)
♦ Presence and Features of Fatty Acyl-CoA Binding Activity of Rat Hepatic Peroxisomes ・・・・・・・・・・・・・・・・・・・・ Hashimoto Fumie / Hayashi Hidenori (25)
♦ Inhibition of cell growth through inactivation of eukaryotic translation initiation factor 5A (eIF5A) by deoxyspergualin ・・・・・・・・・・・・・・・・・・・・ Nishimura K. / Ohki Y. / Fukuchi-Shimogori T. / Sakata K. / Saiga K. / Beppu T. / Shirahata A. / Kashiwagi K. / Igarashi K. (26)
♦ Polyamine structural effects on the induction and stabilization of liquid crystalline DNA : potential applications to DNA packaging, gene therapy and polyamine therapeutics ・・・・・・・・・・・・・・・・・・・・ Saminathan M. / Thomas T. / Shirahata A. / Pillai C. K. S. / Thomas T.J. (27)
♦ Targeting of salicylate to skin and muscle following topical injections in rats ・・・・・・・・・・・・・・・・・・・・ Yoshida Daisuke / Hasegawa Tetsuya / Sugibayashi Kenji (28)
♦ 水晶発振子を用いた薬物のin vitro皮膚透過迅速測定法に関する検討 : Rapid measurement of in vitro skin permeation of a drug using quartz crystal microbalance ・・・・・・・・・・・・・・・・・・・・ 渡邉 哲也/ 長谷川 哲也 / 高橋 秀和 / 石橋 卓也 / 古沢 宏幸 / 岡畑 恵雄 / 杉林 堅次 (29)
♦ Utility of MTT assay in three-dimensional cultured human skin model as an alternative for Draize skin irritation test: Approach using diffusion law of irritant in skin and toxicokinetics-toxicodynamics correlation ・・・・・・・・・・・・・・・・・・・・ Watanabe Tetsuya / Hasegawa Tetsuya / Hidekazu Takahashi / Ishibashi Takuya / Itagaki Hiroshi / Sugibayashi Kenji (30)
♦ Kinetic analysis on the in vitro cytotoxicity using Living Skin Equivalent for ranking the toxic potential of dermal irritants ・・・・・・・・・・・・・・・・・・・・ Sugibayashi Kenji / Watanabe Tetsuya / Hasegawa Tetsuya / Takahashi Hidekazu / Ishibashi Takuya (32)
♦ Bromocriptine Reverses P-Glycoprotein-mediated Multidrug Resistance in Tumor Cells ・・・・・・・・・・・・・・・・・・・・ Shiraki Nobuaki / Okamura Keiko / Tokunaga Jin / Ohmura Takafumi / Yasuda Kazuo / Kawaguchi Takeo / Hamada Akinobu / Nakao Masahiro (33)
♦ N-acetyltransferase 2 genotype-related sulfapyridine acetylation and its adverse events ・・・・・・・・・・・・・・・・・・・・ Tanigawara Y / Kita T / Aoyama N / Gobara M / Komada F / Sakai T / Kasuga M / Hatanaka H / Sakaeda T / Okumura K (34)
♦ Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression ・・・・・・・・・・・・・・・・・・・・ Takara K / Sakaeda T / Tanigawara Y / Nishiguchi K / Ohmoto N / Horinouchi M / Komada F / Ohnishi N / Yokoyama T / Okumura K (36)
♦ In Vitro Skin Permeation of Morphine Hydrochloride during the Finite Application of Penetration-Enhancing System Containing Water, Ethanol and l-Menthol ・・・・・・・・・・・・・・・・・・・・ Morimoto Yasunori / Wada Yoshio / Seki Toshinobu / Sugibayashi Kenji (37)
♦ Effects of Particle Size, Helium Gas Pressure and Microparticle Dose on the Plasma Concentration of Indomethacin after Bombardment of Indomethacin-Loaded Poly-L-Lactic Acid Microspheres Using a HeliosTM Gun System ・・・・・・・・・・・・・・・・・・・・ Uchida Masaki / Natsume Hideshi / Kobayashi Daisuke / Sugibayashi Kenji / Morimoto Yasunori (38)
♦ Introduction of poly-L-lactic acid microspheres into the skin using supersonic flow: effects of helium gas pressure, particle size and microparticle dose on the amount introduced into hairless rat skin ・・・・・・・・・・・・・・・・・・・・ Uchida Masaki / Jin Yi / Natsume Hideshi / Kobayashi Daisuke / Sugibayashi Kenji / Morimoto Yasunori (39)
♦ The Enhancing Effect of a Triethanolamine-Ethanol-Isopropyl Myristate Mixed System on the Skin Permeation of Acidic Drugs ・・・・・・・・・・・・・・・・・・・・ Fang Liang / Kobayashi Yoichi / Numajiri Sachihiko / Kobayashi Daisuke / Sugibayashi Kenji / Morimoto Yasunori (41)
♦ Analysis of Transient and Reversible Effects of Poly-L-Arginine on the in vivo nasal absorption of FITC-dextran in rats ・・・・・・・・・・・・・・・・・・・・ Ohtake Kazuo / Natsume Hideshi / Ueda Hideo / Morimoto Yasunori (42)
♦ Fast-Disintegration Oral Tablets Having Sustained Release Property ・・・・・・・・・・・・・・・・・・・・ Jin Yi / Ohkuma Hideki / Hua Wang / Natsume Hideshi / Sugibayashi Kenji / Morimoto Yasunori (43)
♦ Overlapping of the Clinically Significant Adverse Reactions of Drugs in the Poly-pharmacy ・・・・・・・・・・・・・・・・・・・・ Endo Toshinari / Watanabe Nao / Goto Ken-ichi / Kutsuma Nobuaki / Komada Fusao / Saitoh Yukiya / Kobayashi Daisuke / Morimoto Yasunori (44)
♦ High Performance Liquid Chromatography for Routine Monitoring of Serum Flecainide ・・・・・・・・・・・・・・・・・・・・ Nakagawa Rei / Homma Masato / Koga Keisuke / Yamaguchi Iwao / Kobayashi Daisuke / Morimoto Yasunori / Kohda Yukinao (45)
♦ Current Situation of the Additional Severe Adverse Effects of Marketed Medicine ・・・・・・・・・・・・・・・・・・・・ Kobayashi Daisuke / Kutsuma Nobuaki / Nakayama Megumi / Ukon Atsushi / Sashida Yuko/ Endo Toshinari / Ueda Hideo / Numajiri Sachihiko / Komada Fusao / Saitoh Yukiya / Morimoto Yasunori (46)
♦ Development of a Computer Aided Information System to Provide Information of Adverse Effects to the Patient ・・・・・・・・・・・・・・・・・・・・ Endo Toshinari / Kutsuma Nobuaki / Kobayashi Daisuke / Numajiri Sachihiko / Ueda Hideo / Komada Fusao / Saitoh Yukiya / Morimoto Yasunori (47)
♦ Sex hormone-regulated renal transport of perfluorooctanoic acid ・・・・・・・・・・・・・・・・・・・・ Kudo Naomi / Katakura Masanori / Sato Yasunori / Kawashima Yoichi (48)
♦ Mechanisms of Gastric Mucus Secretion from Cultured Rat Gastric Epithelial Cells Induced by Carbachol, Cholecystokinin Octapeptide, Secretin, and Prostaglandin E2 ・・・・・・・・・・・・・・・・・・・・ Tani Satoru / Suzuki Teruo / Kano Sayuri / Tanaka Toru / Sunaga Katsuyosi / Morisige Rie / Tsuda Tadashi (49)
♦ Postnatal changes in ghrelin mRNA expression and in ghrelin-producing cells in the rat stomach ・・・・・・・・・・・・・・・・・・・・ Sakata I. / Tanaka T. / Matsubara M. / Yamazaki M. / Tani S. / Hayashi Y. / Kangawa K. / Sakai T. (50)
♦ Trifluoromethyl Ketones Show Culture Age-dependent Inhibitory Effects on Low K+-induced Apoptosis in Cerebellar Granule Neurons ・・・・・・・・・・・・・・・・・・・・ Sunaga Katsuyoshi / Tanaka Toru / Tani Satoru / Kawase Masami (51)
♦ Administration of beta-carotene suppresses lipid peroxidation in tissues and improves the glucose tolerance ability of streptozotocin-induced diabetic rats. ・・・・・・・・・・・・・・・・・・・・ Furusho T. / Kataoka E. / Yasuhara T. / Wada M. / Innami S. (52)
♦ Dietary fiber suppresses elevations of uric acid and allantoin in serum and urine induced by dietary RNA and increases its excretion to feces in rats. ・・・・・・・・・・・・・・・・・・・・ Koguchi T / Nakajima H / Wada M / Yamamoto Y / Innami S / Maekawa A / Tadokoro T (53)
♦ Effects of dietary polyamines on the promotion of mammary tumor in rats. ・・・・・・・・・・・・・・・・・・・・ Wada Masahiro / Funada-Wada Ulala / Mano Hiroshi / Higashiguchi Mizuka / Haba Ryouta / Watanabe Shaw / Udaka Shigezo (54)
♦ Effect of partially hydrolyzed curdlan on serum and hepatic cholesterol concentrations, and cecal fermentation in rats. ・・・・・・・・・・・・・・・・・・・・ Shimizu Jun / Oka Masahide / Kudoh Keita / Wada Masahiro / Takita Toshichika / Innami Satoshi / Tadokoro Tadahiro / Maekawa Akio (55)
♦ Dietary curdlan suppresses dimethylhydrazine-induced aberrant crypt foci formation in Sprague-Dawley rats ・・・・・・・・・・・・・・・・・・・・ Shimizu Jun / Kudoh Keita / Wada Masahiro / Takita Toshichika / Innami Satoshi / Maekawa Akio / Tadokoro Tadahiro (56)
♦ Effect of Soy Protein Intake on High-fat induced Obesity and Insulin resistance ・・・・・・・・・・・・・・・・・・・・ Tsunoda Nobuyo / Fujikane Yuko / Kim Hyounju / Ebata Midori / Ikemoto Shinji (57)
♦ 成人のタンパク質必要量に及ぼすエネルギー制限と肥満度の影響 ・・・・・・・・・・・・・・・・・・・・ 池本 真二 / 角田 伸代 / 江端 みどり / 東口 みづか (58)
♦ (平成13年度研究奨励金交付に伴う研究成果報告書)骨折及び骨粗鬆症の分子生物学的解析とその栄養学的予防法確立に関する研究 ・・・・・・・・・・・・・・・・・・・・ (研究代表者)和田 政裕 (59)
♦ 研究題目 医薬品の乳汁移行性予測に関する研究 ・・・・・・・・・・・・・・・・・・・・ 小林 大介 / 沼尻 幸彦 (66)
♦ 口頭発表及びシンポジウム ・・・・・・・・・・・・・・・・・・・・ (75)
♦ 著書・総説・Proceedings類 ・・・・・・・・・・・・・・・・・・・・ (96)
♦ (学位論文要旨) 博士(薬学) 高速気体を利用した薬物含有微粒子の皮内送達に関する研究 ・・・・・・・・・・・・・・・・・・・・ (103)
♦ (学位論文要旨) 博士(薬学)(課程) 水溶性高分子の鼻粘膜吸収に対するポリ-L-アルギニンの促進機構に関する研究 ・・・・・・・・・・・・・・・・・・・・ (106)
♦ 多成分油性基剤を用いた酸性薬物の皮膚透過促進に関する研究 ・・・・・・・・・・・・・・・・・・・・ 方 亮 (108)
♦ 大学院薬学研究科修士論文要旨 ・・・・・・・・・・・・・・・・・・・・ (113)

城西大学