| ♦ Study of chiral recognition of bilayered phosphatidylcholine vesicles using a helicene probe : Characteristic function of cholesterol. | ・・・・・・・・・・・・・・・・・・・・ | Nakagawa Hiroko / Yoshida Maiko / Kobori Yuuki / Yamada Koh-ichi (1) |
| ♦ STM observation of molecular chirality and alignment on solid surface. | ・・・・・・・・・・・・・・・・・・・・ | Taniguchi Masahiro / Nakagawa Hiroko / Yamagishi Akihiro / Yamada Koh-ichi (2) |
| ♦ Helical assembly formed by chiral [11]thiaheterohelicene in crystals. Architecture with triple helix. | ・・・・・・・・・・・・・・・・・・・・ | Nakagawa Hiroko / Yoshino Jun / Yamada Koh-ichi / Shiro Mutoo (3) |
| ♦ O-Allylic Substitution of Hydroxylamine Derivatives Having an N-Electron-Withdrawing Substituent | ・・・・・・・・・・・・・・・・・・・・ | Miyake Hideto / Yoshida Kazumasa / Matsumura Akira / Yamauchi Masashige / Takemoto Yoshiji (4) |
| ♦ Synthesis of Spiro-Fused Nitrogen Heterocyclic Compounds via N-Methoxy-N-acylnitrenium Ions Using Phenyliodine (III) Bis(trifluoroacetate) in Trifluoroethanol | ・・・・・・・・・・・・・・・・・・・・ | Miyazawa Etsuko / Sakamoto Takeshi / Kikugawa Yasuo (5) |
| ♦ Synthesis of Spirodienones by Intramolecular Ipso-Cyclization of Using N-Methoxy-(4-halogenophenyl)amides [Hydroxy(tosyloxy)iodo]benzene in Trifluoroethanol | ・・・・・・・・・・・・・・・・・・・・ | Miyazawa Etsuko / Sakamoto Takeshi / Kikugawa Yasuo (6) |
| ♦ Intramolecular Cyclization with Nitrenium Ions Generated by Treatment of N-Acylaminophthalimides with Hypervalent Iodine Compounds: Formation of Lactams and Spiro-Fused Lactams | ・・・・・・・・・・・・・・・・・・・・ | Kikugawa Yasuo / Nagashima Akira / Sakamoto Takeshi / Miyazawa Etsuko / Shiiya Megumi (7) |
| ♦ A Convenient Synthesis of 1-Alkylhydrazines And 1-Alkyl-1-phenylhydrazines from N-Aminophthalimide | ・・・・・・・・・・・・・・・・・・・・ | Nara Shigeru / Sakamoto Takeshi / Miyazawa Etsuko / Kikugawa Yasuo (8) |
| ♦ Structural requirements of hydroxylated coumarins for in vitro anti-Helicobacter pylori activity. | ・・・・・・・・・・・・・・・・・・・・ | Kawase M. / Tanaka T. / Sohara Y. / Tani S. / Sakagami H. / Hauer H. / Chatterjee S.S. (9) |
| ♦ Enhancement of plasmid curing by 9-aminoacridine and two phenothiazines in the presence of proton pump inhibitor 1-(2-benzoxazolyl)-3,3,3-trifluoro-2-propanone | ・・・・・・・・・・・・・・・・・・・・ | Spengler G. / Miczak A. / Hajdu E. / Kawase M. / Amaral L. / Molnar J. (10) |
| ♦ Antimicrobial activity of N-acylphenothiazines and their influence on lipid model membranes and erythrocyte membranes. | ・・・・・・・・・・・・・・・・・・・・ | Motohashi N. / Kawase M. / Molnar J. / Ferenczy L. / Wesolowska O. / Hendrich A.B. / Bobrowska-Hagerstrand M. / Hagerstrand H. / Michalak K. (11) |
| ♦ Effect of antisense oligodeoxynucleotide for sepiapterin reductase on the viability of PC12 cells in the presence of exogenous carbonyl compounds | ・・・・・・・・・・・・・・・・・・・・ | Fujimoto K. / Sakurai M. / Kawase M. / Katoh S. (12) |
| ♦ Comparative analysis of apoptosis-inducing activity of codeine and codeinone. | ・・・・・・・・・・・・・・・・・・・・ | Hitosugi N. / Hatsukari I. / Ohno R. / Hashimoto K. / Mihara S. / Mizukami S. / Nakamura S. / Sakagami H. / Nagasaka H. / Matsumoto I. / Kawase M. (13) |
| ♦ Analysis of apoptosis signaling pathway in human cancer cells by codeinone, a synthetic derivative of codeine. | ・・・・・・・・・・・・・・・・・・・・ | Hitosugi N. / Nagasaka H. / Sakagami H. / Matsumoto I. / Kawase M. (14) |
| ♦ Structure-cytotoxic activity relationships of simple hydroxylated coumarins. | ・・・・・・・・・・・・・・・・・・・・ | Kawase M. / Sakagami H. / Hashimoto K. / Tani S. / Hauer H. / Chatterjee S.S. (15) |
| ♦ Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by Barbados cherry, a fruit of Malpighia emarginata DC | ・・・・・・・・・・・・・・・・・・・・ | Wakabayashi H. / Fukushima H. / Yamada T. / Kawase M. / Shirataki Y. / Satoh K. / Tobe T. / Hashimoto K. / Kurihara T. / Motohashi N. / Sakagami H. (16) |
| ♦ Biological activity of persimmon (Diospyros kaki) peel extracts | ・・・・・・・・・・・・・・・・・・・・ | Kawase M. / Motohashi N. / Satoh K. / Sakagami H. / Nakashima H. / Tani S. / Shirataki Y. / Kurihara T. / Spengler G. / Wolfard K. / Molnar J. (17) |
| ♦ Multidrug resistance reversal in mouse lymphoma cells by Indian tea leaves, Indian coffee seeds and chicory. | ・・・・・・・・・・・・・・・・・・・・ | Rao B.K. / Motohashi N. / Kawase M. / Spengler G. / Molnar J. (18) |
| ♦ Spongistatin Synthetic Studies. An Efficient, Second-Generation Construction of an Advanced ABCD Intermediate | ・・・・・・・・・・・・・・・・・・・・ | Smith Amos B. III / Doughty Victoria A. / Sfouggatakis Chris / Bennett Clay S. / Koyanagi Junichi / Takeuchi Makoto (19) |
| ♦ Six Flavonostilbenes from Gnetum africanum and Gnetum gnemon | ・・・・・・・・・・・・・・・・・・・・ | Iliya Irbahim / Tanaka Toshiyuki / Ali Zulfiqar / Iinuma Muenekazu / Furusawa Miyuki / Nakaya Ken-ichi / Shirataki Yoshiaki / Murata Jin / Darnaedi Dedy / Matuura Mobuyasu / Ubukata Makoto (20) |
| ♦ Three New Trimeric Stilbenes from Gnetum gnemon. | ・・・・・・・・・・・・・・・・・・・・ | Iliya Irbahim / Ali Zulfiqar / Tanaka Toshiyuki / Iinuma Muenekazu / Furusawa Miyuki / Nakaya Ken-ichi / Shirataki Yoshiaki / Murata Jin / Darnaedi Dedy / Matsuura Nobuyasu / Ubukata Makoto (21) |
| ♦ Cytotoxic and Multidrug Resistance Reversal Activity of a Vegetable, `Anastasia Red', a Variety of Sweet Pepper | ・・・・・・・・・・・・・・・・・・・・ | Motohashi Noboru / Wakabayashi Hidetsugu / Kurihara Teruo / Takada Yuko / Maruyama Shichiro / Sakagami Hiroshi / Nakashima Hideki / Tani Satoru / Shirataki Yoshiaki / Kawase Masami / Wolfard Kristina / Molnar Joseph (23) |
| ♦ New resveratrol oligomers in the stem bark of Vatica pauciflora | ・・・・・・・・・・・・・・・・・・・・ | Ito Tetsuro / Tanaka Toshiyuki / Iinuma Munekazu / Iliya Ibrahim / Nakaya Ken-ichi / Ali Zulfiqar / Takahashi Yoshiakazu / Sawa Ryuichi / Shirataki Yoshiaki / Murata Jin / Darnaedi Dedy (23) |
| ♦ Flavonoids as Inhibitors of MRP1-like Efflux Activity in Human Erythrocytes.A Structure-Activity Relationship Study | ・・・・・・・・・・・・・・・・・・・・ | Bobrowska-Hagerstrand Malgorzata / Wrobel Anna / Mrowczynska Lucyna / Soderstrom Thomas / Shirataki Yoshiaki / Motohashi Noboru / Molnar Joseph / Michalak Krystyna / Hagerrstrand Henry (24) |
| ♦ Functional baioactivity of Polygonatum species | ・・・・・・・・・・・・・・・・・・・・ | Motohashi Noboru / Zang Guo-Wen / Shirataki Yoshiaki (25) |
| ♦ Fate of Orally Administered 15N-Labeled Polyamines in Rats Bearing Solid Tumors | ・・・・・・・・・・・・・・・・・・・・ | Kobayashi Masaki / Yong Ji Xu / Samejima Keijiro / Goda Hitomi / Niitsu Masaru / Takahashi Masakazu / Hashimoto Yoshiyuki (26) |
| ♦ Synthetic Decarboxylated S-Adenosyl-L-methionine as a Substrate for Aminopropyl Transferases | ・・・・・・・・・・・・・・・・・・・・ | Dejima Hideki / Kobayashi Masaki / Takasaki Hideki / Takeda Noboru / Shirahata Akira / Samejima Keijiro (27) |
| ♦ Relative Reactivities of Histamine and Indoleamines with Acetaldehyde | ・・・・・・・・・・・・・・・・・・・・ | Ohya Takeshi / Niitsu Masaru (28) |
| ♦ Changes in intracellular concentrations of polyamines during apoptosis of HL-60 cells | ・・・・・・・・・・・・・・・・・・・・ | Nakamura C. / Yasumoto E. / Nakano K. / Nakayachi T. / Hashimoto K. / Kusama K. / Fukuda M. / Sakashita H. / Shirahata A. / Sakagami H. (29) |
| ♦ Effects of Peroxisome Proliferators Gemfibrozil and Clofibrate on Syntheses of Dolichol and Cholesterol in Rat Liver | ・・・・・・・・・・・・・・・・・・・・ | Shiota Yasuo / Ikeda Masatoshi / Hashimoto Fumie / Hayashi Hidenori (30) |
| ♦ Urease inhibitory activity of simple alpha,beta-unsaturated ketones. | ・・・・・・・・・・・・・・・・・・・・ | Tanaka T. / Kawase M. / Tani S. (31) |
| ♦ Possible correlation between abilities of a variety of polyamines to increase activator protein -1 DNA binding and to inhabit [3H]spermidine transport in nuclear fractions of murine brain. | ・・・・・・・・・・・・・・・・・・・・ | ////// Shirahata Akira / (32) |
| ♦ X-linked spermine synthase gene (SMS) defect: the first polyamine deficiency syndrome. | ・・・・・・・・・・・・・・・・・・・・ | Cason A.Lauren / Ikeguchi Yoshihiko / Skinner Cindy / Wood Tim C. / Holden Kenton R. / Lubs Herbert A. / Martinez Francisco / Simensen Richard J. / Stevenson Roger E. / Pegg Anthony E. / Schwartz Charies E. (33) |
| ♦ Effect of spermine synthase on the sensitivity of cells anti-tumour agents | ・・・・・・・・・・・・・・・・・・・・ | Ikeguchi Yoshihiko / Mackintosh.Caroline A. / McCloskey Diane E. / Pegg Anthony E. (34) |
| ♦ Structural and serological characterization of 5,7-diamino-3,5,7,9-tetradeoxy- non-2-ulosonic acid isolated from lipopolysaccharides of Vibrio parahaemolyticus O2 and O-untypeable strain KX-V212 | ・・・・・・・・・・・・・・・・・・・・ | Hashii Noritaka / Isshiki Yasunori / Iguchi Takehiro / Hitsatsune Kazuhito / Kondo Seiichi (35) |
| ♦ Structural analysis of the carbohydrate backbone of Vibrio parahaemolyticus O2 lipopolysaccharides | ・・・・・・・・・・・・・・・・・・・・ | Hashimoto Noritaka / Isshiki Yasunori / Iguchi Takehiro / Kondo Seiichi (37) |
| ♦ Structural characterization of the carbohydrate backbone of the lipopolysaccharide of Vibrio parahaemolyticus O-untypeable strain KX-V212 isolated from a patient | ・・・・・・・・・・・・・・・・・・・・ | Hashimoto Noritaka / Isshiki Yasunori / Iguchi Takehiko / Kondo Seiichi (37) |
| ♦ Adaptive and inflammatory immune responses in patients infected with strains of Vibrio parahaemolyticus | ・・・・・・・・・・・・・・・・・・・・ | Quadri F. / Alam MS. / Nishibuchi M. / Alam MH. / Christi J. / Kondo Seiichi / Sugiyama J. / Bhuiyan NA. / Mathan MM. / Sack DA. / Nair GB. (38) |
| ♦ A survey on pharmaceutical information in daily newspapers | ・・・・・・・・・・・・・・・・・・・・ | Onobori Yukiko / Komada Fusao / Saitoh Yukiya (39) |
| ♦ Induction of CYP3As in HepG2 Cells by Several Drugs. - Association between Induction of CYP3A4 and Expression of Glucocorticoid Receptor -. | ・・・・・・・・・・・・・・・・・・・・ | Usui T. / Saitoh Y. / Komada F. (40) |
| ♦ Effect of chondroitin sulfate on the diffusion coefficients of drugs in aqueous solutions | ・・・・・・・・・・・・・・・・・・・・ | / Okamoto Maiko // Aiba Daiki // Juni Kazuhiko (42) |
| ♦ Measurement of diffusion coefficients of parabens and steroids in water and 1-octanol | ・・・・・・・・・・・・・・・・・・・・ | Seki Toshinobu / Mochida Junko / Okamoto Maiko / Hosoya Osamu / Juni Kazuhiko / Morimoto Kazuhiro (44) |
| ♦ Poly-L-arginine predominantly increases the paracellular permeability of hydrophilic macromolecules across rabbit nasal epithelium in vitro | ・・・・・・・・・・・・・・・・・・・・ | Ohtake Kazuo / Maeno Takuya / Ueda Hideo / Natsume Hideshi / Morimoto Yasunori (45) |
| ♦ 学内LANを利用した実習希望施設エントリーシステムの構築とその評価 | ・・・・・・・・・・・・・・・・・・・・ | 沼尻 幸彦 / 上田 秀雄 / 小林 大介 / 森本 擁憲 // (47) |
| ♦ Area distribution of out-issued prescriptions from Saiseikai Kurihashi Hospital and behavior patterns of outpatients for selection of pharmacy | ・・・・・・・・・・・・・・・・・・・・ | / Tsuchida Saori /// Ueda Hideo / Numajiri Sachihiko / Kobayashi Daisuke / Morimoto Yasunori (48) |
| ♦ The use of complexation with alkanolamines to facilitate skin permeation of mefenamic acid | ・・・・・・・・・・・・・・・・・・・・ | Fang Liang / Numajiri Sachihiko / Kobayashi Daisuke / Morimoto Yasunori (49) |
| ♦ Characterization of Transdermal Solute Transport Induced by Low-Frequency Ultrasound in the Hairless Rat Skin | ・・・・・・・・・・・・・・・・・・・・ | Mutoh Mizue / Ueda Hideo / Nakamura Yasushi /// Kobayashi Daisuke / Morimoto Yasunori (50) |
| ♦ The effects of calcium chloride and sodium chloride on the electroporation-mediated skin permeation of fluorescein isothiocyanate (FITC)-dextrans in vitro | ・・・・・・・・・・・・・・・・・・・・ | Tokudome Yoshihiro / Sugibayashi Kenji (52) |
| ♦ The synergic effects of various electrolytes and electroporation on the in vitro skin permeation of calcein | ・・・・・・・・・・・・・・・・・・・・ | Tokudome Yoshihiro / Sugibayashi Kenji (53) |
| ♦ Effect of electric field on the enhanced skin permeation of drugs by electroporation | ・・・・・・・・・・・・・・・・・・・・ | / Hasegawa Tetsuya // Sugibayashi Kenji (54) |
| ♦ Poly-L-arginine enhances paracellular permeability via serine/threonine phosphorylation of ZO-1 and tyrosine dephosphorylation of occludin in rabbit nasal epithelium | ・・・・・・・・・・・・・・・・・・・・ | Ohtake Kazuo / Maeno Tetsuya / Ueda Hideo / Ogiwara Masahiko / Natsume Hideshi / Morimoto Yasunori (55) |
| ♦ Design and feasibility assessment of topically applied drug formulations for electroporation | ・・・・・・・・・・・・・・・・・・・・ | ////// Sugibayashi Kenji (57) |
| ♦ Effects of hardness on decoction of Chinese medicine | ・・・・・・・・・・・・・・・・・・・・ | Honma Seiichi / Ogawa Akihiko / Kobayashi Daisuke / Ueda Hideo / Fang Liang / Numajiri Sachihiko / Kimur Masayuki / Terasawa Katsutoshi / Morimoto Yasunori (58) |
| ♦ Comparison of drug prices between extracts and decoctions of Chinese medicine as ethical pharmaceuticals considering dispensing free and contents of index ingredients | ・・・・・・・・・・・・・・・・・・・・ | Honma Seiichi / Hirota Hajime / kobayashi Daisuke / Ueda Hideo / Numajiri Sachihiko / Komada Fusao / Saito Yukiya / Morimoto Yasunori (60) |
| ♦ 処方せん情報の医薬品開発へのフィードバック2 経口徐放性製剤の適正使用について | ・・・・・・・・・・・・・・・・・・・・ | 金 素安 / 田澤 悠子 / 長谷川 哲也 / 小林 大介 / 井上 直子 / 田利 多加子 / 木村 昌行 / 山本 俊行 / 山口 正俊 / 杉林 堅次 (62) |
| ♦ Liquid chromatographic determination of unbound flecainide in therapeutic drug monitoring | ・・・・・・・・・・・・・・・・・・・・ | Katori Kumi / Homma M. / Kuga K. / Yamaguchi I / Sugibayashi Kenji / Kohda Y. (64) |
| ♦ Postnatal Changes and effects of glucocorticoid on MUC5AC mRNA expression in the rat stomach. | ・・・・・・・・・・・・・・・・・・・・ | Tanaka Tohru / Tani Satoru (65) |
| ♦ Induction of Triglyceride Accumulation in the Liver of Rats by Perfluorinated Fatty Acids with Different Carbon Chain Lengths: Comparison with Induction of Peroxisomal β-Oxidation | ・・・・・・・・・・・・・・・・・・・・ | Kudo Naomi / Kawashima Yoichi (66) |
| ♦ Comparison of the Toxicokinetics between perfluorocarboxylic acids with Different Carbon Chain Length | ・・・・・・・・・・・・・・・・・・・・ | Ohmori Kohtaro / Kudo Naomi / Katayama Kazunori / Kawashima Yoichi (67) |
| ♦ Sex Hormone Regulation of Rat Organic Anion Transporter3 (rOAT3) Expression in Rat Kidney | ・・・・・・・・・・・・・・・・・・・・ | Katakura Masanori / Kudo Naomi / Okazaki Mari / Hibino Yasuhide / Kawashima Yoichi (68) |
| ♦ Effects of Dehydroepiandrosterone on Oleic Acid Accumulation in Rat Liver | ・・・・・・・・・・・・・・・・・・・・ | Imai Koichi / Kudo Naomi / Koyama Matajirou / Kawashima Yoichi (69) |
| ♦ Regulation by Carbohydrate and Clofibric Acid of Palmitoyl coA chain Elongation in the Liver of Rats | ・・・・・・・・・・・・・・・・・・・・ | Kudo Naomi / Toyama Tomoaki / Mitsumoto Atsushi / Kawashima Yoichi (70) |
| ♦ Age-Period-Cohortモデルによる日本人中高年の損失寿命に関する分析 | ・・・・・・・・・・・・・・・・・・・・ | 小田切 陽一 / 内田 博之 (71) |
| ♦ A low fish oil inhibits SREBP-1 proteolytic cascade, while a high-fish-oil feeding decreases SREBP-1 mRNA in mice liver: relationship to anti-obesity. | ・・・・・・・・・・・・・・・・・・・・ | Nakatani T / Kim HJ / Kaburagi Y / Yasuda K / Ezaki O (72) |
| ♦ Puerariase radix prevents bone loss in ovariectomized mice. | ・・・・・・・・・・・・・・・・・・・・ | Wang Xinxiang / Wu Jian / Chiba Hiroshige / Uegami Keizo / Yamada Kazuhiko / Ishimi Yoshiko (73) |
| ♦ Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice. | ・・・・・・・・・・・・・・・・・・・・ | Chiba Hiroshige / Uehara Mariko / Wu Jian / Wang Xinxiang / Matsuyama Ritsuko / Suzuki Kazuharu / Kanazawa Kazuki / Ishimi Yoshiko (74) |
| ♦ Androgen Deficiency-induced Bone Loss Can Be Prevented by the Combined Intervention of Exercise and Genistein Administration in Mice. | ・・・・・・・・・・・・・・・・・・・・ | Wu Jian / Wang Xin Xiang / Chiba Hiroshige / Higuchi Mitsuru / Takasaki Misao / Ohta Atsutane / Ishimi Yoshiko (76) |
| ♦ Food and nutrient intakes assessed with dietary records for the validation study of a self-administered food frequency questionnaire in JPHC Study Cohort I. | ・・・・・・・・・・・・・・・・・・・・ | Sasaki S. / Takahashi T. / Iitoi Y / Iwase Y. / Kobayashi M. / Ishihara J. / Akabane M. / Tsugane S. (77) |
| ♦ (平成12年度学長所管 研究テーマ) 「胃潰瘍原因菌 : Helicobacter pylori のラットへの感染に関する基礎的検討、並びに抗菌物質の探索」 | ・・・・・・・・・・・・・・・・・・・・ | 谷 覺 / 白瀧 義明 / 河瀬 雅美 (78) |
| ♦ (平成14年度学長所管研究奨励金交付に伴う研究) 研究課題 食品成分中のポリアミンによる腸管吸収の修飾 | ・・・・・・・・・・・・・・・・・・・・ | 杉田 義昭 (81) |
| ♦ 研究題目 イオントフォレシスによる抗白内障薬ジスルフィラムの眼組織送達に関する研究 | ・・・・・・・・・・・・・・・・・・・・ | 上田 秀樹 (84) |
| ♦ 口頭発表及びシンポジウム | ・・・・・・・・・・・・・・・・・・・・ | (91) |
| ♦ 著書・総説・Proceedings類 | ・・・・・・・・・・・・・・・・・・・・ | (109) |
| ♦ (学位論文要旨)腸炎ビブリオO抗原リポ多糖(LPS)の化学的および血清学的性状に関する研究 | ・・・・・・・・・・・・・・・・・・・・ | 橋井 則貴 (113) |
| ♦ (学位論文要旨) キトサンの経皮吸収型製剤のためのゲル基剤への応用に関する研究 | ・・・・・・・・・・・・・・・・・・・・ | 佐野 元彦 (116) |
| ♦ (学位論文要旨) 親水性化合物の経皮吸収促進のための超音波の利用に関する研究 | ・・・・・・・・・・・・・・・・・・・・ | 武藤 香絵 (118) |
| ♦ (学位論文要旨) エレクトロポレーションによる薬物の経皮吸収促進に関する研究 | ・・・・・・・・・・・・・・・・・・・・ | 森 健二 (121) |
| ♦ 大学院薬学研究科修士論文要旨 | ・・・・・・・・・・・・・・・・・・・・ | (123) |
| ♦ 著者索引 | ・・・・・・・・・・・・・・・・・・・・ | (151) |