城西大学機関リポジトリJURAMultidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells

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Multidrug resistance reversal by 3-formylchromones in human colon cancer and human mdr1 gene-transfected mouse lymphoma cells

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ID	JOS-0258851X-20-645
著者：名前	Barath, Zoltan/Radics, Rita/Spengler, Gabriella/Ocsovszki, Imre/河瀬, 雅美/本橋, 登/白瀧, 義明/Shah, Anamik/Molnar, Jozsef
著者：別形式	Barath, Zoltan / Radics, Rita / Spengler, Gabriella / Ocsovszki, Imre / Kawase, Masami / Motohashi, Noboru / Shirataki, Yoshiaki / Shah, Anamik / Molnar, Jozsef
著者：カナ	カワセ, マサミ/モトハシ, ノボル/シラタキ, ヨシアキ
著者：所属	University of Szeged, Faculty of General Medicine, Department of Medical Microbiology and Immunobiology / University of Szeged, Faculty of General Medicine, Department of Medical Microbiology and Immunobiology / University of Szeged, Faculty of General Medicine, Department of Medical Microbiology and Immunobiology / Albert Szent-Gyorgyi Medical University, Institute of Biochemistry / 城西大学薬学部 / 明治薬科大学 / 城西大学薬学部 / Saurashtra University, Department of Chemistry / University of Szeged, Faculty of General Medicine, Department of Medical Microbiology and Immunobiology
著者：所属(別形式）	University of Szeged, Faculty of General Medicine, Department of Medical Microbiology and Immunobiology / University of Szeged, Faculty of General Medicine, Department of Medical Microbiology and Immunobiology / University of Szeged, Faculty of General Medicine, Department of Medical Microbiology and Immunobiology / Albert Szent-Gyorgyi Medical University, Institute of Biochemistry / Josai University, Faculty of Pharmaceutical Sciences / Meiji Pharmaceutical University, Department of Pharmaceutical Sciences / Josai University, Faculty of Pharmaceutical Sciences / Saurashtra University, Department of Chemistry / University of Szeged, Faculty of General Medicine, Department of Medical Microbiology and Immunobiology
著者版フラグ	publisher
出版地	Athens
出版者	International Institute of Anticancer Research
NCID	AA10714348
冊子ISSN	0258851X
掲載誌名	In Vivo : International Journal of Experimental and Clinical Pathophysiology of Drug Research
巻	20
号	5
刊行年月	2006-09
開始ページ	645
終了ページ	649
コンテンツ作成日	2006-07-07
コンテンツ登録日	2011-07-31
抄録	Several new 3-formylchromone derivatives proved to be modifiers of multidrug resistance in mouse lymphoma cells and in human Colo320 colon cancer cells. There is apparently a structure-activity relationship between the antiproliferative multidrug resistance-reversing effect and the chemical structure of the 3-formylchromones. The total polar surface areas and the ground state dipole moments of the molecules are presumed to play a key role in the multidrug resistance-reversing effect. The log P values can provide an adequate explanation for the selective cytotoxicity against cancer cells.
キーワード	Formylchromones/multidrug resistance-reversing effect
注記	5p.
言語	eng
資源タイプ	text
ジャンル	01学術雑誌論文 / Journal Article
フォーマット	application/pdf
このアイテムを表示する：本文(pdf)	( 1.2MB) ダウンロード回数：回
このアイテムを表示する：URI	http://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-0258851X-20-645

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