ID | JOS-20902077_2019_7530480 |
著者:名前 | |
著者:別形式 | Ezawa, Toshinari / Inoue, Yutaka / Murata, Isamu / Takao, Koichi / Sugita, Yoshiaki / Kanamoto, Ikuo |
著者:カナ | |
著者:所属 | 城西大学薬学部薬学科医薬品安全性学研究室 / 城西大学薬学部薬学科医薬品安全性学研究室 / 城西大学薬学部薬学科医薬品安全性学研究室 / 城西大学薬学部薬科学科生物有機化学研究室 / 城西大学薬学部薬科学科生物有機化学研究室 / 城西大学薬学部薬学科医薬品安全性学研究室 |
著者:所属(別形式) | Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, Laboratory of Drug Safety Management / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, Laboratory of Drug Safety Management /Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, Laboratory of Drug Safety Management / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, Laboratory of Bioorganic Chemistry / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, Laboratory of Bioorganic Chemistry / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, Laboratory of Drug Safety Management |
著者版フラグ | publisher |
出版者 | Hindawi Publishing Corporation |
冊子ISSN | 20902069 |
電子ISSN | 20902077 |
掲載誌名 | |
巻 | 2019 |
号 | Article ID 7530480 |
開始ページ | 1 |
終了ページ | 14 |
コンテンツ作成日 | 2018-12-18 |
コンテンツ修正日 | 2019-01-27 |
コンテンツ登録日 | 2019-04-26 |
識別番号:DOI | info:doi/10.1155/2019/7530480 |
識別番号:DOI(リンク) | |
PubMed番号 | 30886749 |
抄録 | The purpose of this study was to evaluate the physicochemical properties of piperine (PP) in ground mixtures (GMs) of PP with α-, β-, or γ-cyclodextrin (CD) under conditions of humidity, heat, and humidity-heat. In solid-state fluorescence measurements, the fluorescence maxima for GM (PP/αCD = 1/2), GM (PP/βCD = 1/1), and GM (PP/γCD = 1/1) were observed at 463, 472, and 469 nm, respectively. On the other hand, the humidified GMs exhibited maxima at 454, 460, and 465 nm, while the humidified-heated samples displayed fluorescence maxima at 455, 455, and 469 nm, respectively. Therefore, the molecular behavior of PP with α, β, and γCD was concluded to vary upon the coordination of water molecules. NIR and solid-state fluorescence measurements revealed that the molecular behavior of PP inside the α, β, and γCD cavity changed by water and heat factors depends on the mobility of the methylenedioxyphenyl group. |
キーワード | |
注記 | This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
言語 | eng |
資源タイプ | text |
ジャンル | |
フォーマット | application/pdf |
権利 | Copyright © 2019 Toshinari Ezawa et al. |
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