| ID | JOS-fba.2018-00080 |
| 著者：名前 | |
| 著者：別形式 | Kobayashi, Jun / Uchida, Hiroyuki / Kofuji, Ayaka / Ito, Junta / Shimizu, Maki / Kim, Hyounju / Sekiguchi, Yusuke / Kushibe, Seiji |
| 著者：カナ | |
| 著者：所属 | 城西大学薬学部医療栄養学科 / 城西大学薬学部医療栄養学科 / 城西大学薬学部医療栄養学科 / 城西大学薬学部医療栄養学科 / 城西大学薬学部医療栄養学科 / 城西大学薬学部医療栄養学科 / 城西大学薬学部医療栄養学科 / 城西大学経営学部マネジメント総合学科 |
| 著者：所属(別形式） | Josai University, Faculty of Pharmacy and Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Pharmacy and Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Pharmacy and Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Pharmacy and Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Pharmacy and Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Pharmacy and Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Pharmacy and Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Management, Department of Management |
| 著者版フラグ | publisher |
| 出版地 | Hoboken |
| 出版者 | Wiley |
| 電子ISSN | 25739832 |
| 掲載誌名 | |
| 巻 | 1 |
| 号 | 6 |
| 刊行年月 | 2019-06 |
| 開始ページ | 364 |
| 終了ページ | 374 |
| コンテンツ作成日 | 2018-12-21 |
| コンテンツ修正日 | 2019-03-13 |
| コンテンツ登録日 | 2019-07-30 |
| 識別番号：DOI | info:doi/10.1096/fba.2018-00080 |
| 識別番号：DOI（リンク） | |
| 抄録 | A variety of internal and external factors such as exercise, nutrition, inflammation, and cancer‐associated cachexia affect the regulation of skeletal muscle mass. Because skeletal muscle functions as a crucial regulator of whole body metabolism, rather than just as a motor for locomotion, the enhancement and maintenance of muscle mass and function are required to maintain health and reduce the morbidity and mortality associated with diseases involving muscle wasting. Recent studies in this field have made tremendous progress; therefore, identification of the mechanisms that regulate skeletal muscle mass is necessary for the physical and nutritional management of both athletes and patients with muscle wasting disease. In this review, we present an overall picture of the interactions regulating skeletal muscle mass, particularly focusing on the insulin‐like growth factor‐I (IGF‐I)/insulin‐Akt‐mammalian target of rapamycin (mTOR) pathway, skeletal muscle inactivity, and endurance and resistance exercise. We also discuss the contribution of nitric oxide (NO) to the regulation of skeletal muscle mass based on the current knowledge of the novel role of NO in these processes. |
| キーワード | |
| 注記 | This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
| 言語 | eng |
| 資源タイプ | text |
| ジャンル | |
| フォーマット | application/pdf |
| 権利 | Copyright © 2019 The Authors. |
| このアイテムを表示する：本文(pdf) |  ( 1.0MB) ダウンロード回数： 回 |
| このアイテムを表示する：URI | |
