城西大学機関リポジトリJURACombined effects of soy isoflavone and fish oilon ovariectomy-induced bone loss in mice

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Combined effects of soy isoflavone and fish oilon ovariectomy-induced bone loss in mice

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ID	JOS-s00774-010-0234-8
著者：名前	内田, 礼奈/千葉, 大成/石見, 佳子/上原, 万里子/鈴木, 和春/金, 賢珠/松本, 明世
著者：別形式	Uchida, Raina / Chiba, Hiroshige / Ishimi, Yoshiko / Uehara, Mariko / Suzuki, Kazuharu / Kim, Hyounju / Matsumoto, Akiyo
著者：カナ	ウチダ, ライナ/チバ, ヒロシゲ/イシミ, ヨシコ/ウエハラ, マリコ/スズキ, カズハル/キム, ヒョンジュ/マツモト, アキヨ
著者：所属	城西大学薬学部医療栄養学科 / 城西大学薬学部医療栄養学科 / 国立健康・栄養研究所 / 東京農業大学栄養科学科 / 東京農業大学栄養科学科 / 城西大学薬学部医療栄養学科 / 城西大学薬学部医療栄養学科
著者：所属(別形式）	Josai University, Faculty of Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / National Institute of Health and Nutrition, Nutritional Epidemiology Program / Tokyo University of Agriculture, Department of Nutritional Science / Tokyo University of Agriculture, Department of Nutritional Science / Josai University, Faculty of Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition / Josai University, Faculty of Pharmaceutical Science, Department of Clinical Dietetics and Human Nutrition
著者版フラグ	author
出版地	京都
出版者	日本骨代謝学会
出版者：カナ	ニホンコツタイシャガッカイ
出版者：別名	The Japanese Society for Bone and Mineral Research
NCID	AA10747551
冊子ISSN	09148779
電子ISSN	14355604
掲載誌名	Journal of Bone and Mineral Metabolism
巻	29
号	4
刊行年月	2011-07
開始ページ	404
終了ページ	413
コンテンツ作成日	2010-09-21
コンテンツ登録日	2011-08-03
識別番号：DOI	info:doi/10.1007/s00774-010-0234-8
識別番号：DOI（リンク）	https://doi.org/10.1007/s00774-010-0234-8
PubMed番号	21069546
NII論文ID	120005518468
識別番号：その他	1050282677766390656
抄録	Both soy isoflavone and n-3 polyunsaturatedfatty acids are known to reduce the levels of bone-resorbingcytokines; however, the synergistic effects of these foodingredients have not been examined yet. This study wasperformed to elucidate the effect of concomitant intake ofsoy isoflavone and fish oil on bone mass in ovariectomizedmice. Eight-week-old ddY female mice were subjectedto ovariectomy (OVX) or sham surgery, and then fed anAIN-93G with safflower oil (So) as a control lipid source,isoflavone-supplemented safflower oil (So ? I), fish oilinstead of safflower oil (Fo) or isoflavone-supplemented fishoil (Fo ? I) for 4 weeks. Femoral bone mineral density wassignificantly decreased by OVX; however, this decrease wasinhibited by the intake of isoflavone and/or fish oil. Histomorphometricanalyses showed that bone volume and trabecularthickness in the distal femoral trabecular bone weresignificantly lower in the So group than in the sham group,but those were restored in the Fo ? I groups. The number ofosteoclasts was significantly decreased by isoflavone intake
キーワード	Bone-resorbing cytokines/Flavonoid/Polyunsaturated fatty acids/Osteoporosis
注記	Original article. オンライン版はSpringerLinkで The Japanese Society for Bone and Mineral Research and Springer 2010. 45p.
言語	eng
資源タイプ	text
ジャンル	01学術雑誌論文 / Journal Article
フォーマット	application/pdf
このアイテムを表示する：本文(pdf)	( 1.0MB) ダウンロード回数：回
このアイテムを表示する：URI	http://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-s00774-010-0234-8

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