城西大学機関リポジトリJURACannabidiol Content and In Vitro Biological Activities of Commercial Cannabidiol Oils and Hemp Seed Oils

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Cannabidiol Content and In Vitro Biological Activities of Commercial Cannabidiol Oils and Hemp Seed Oils

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ID	JOS-medicines7090057
著者：名前	北村, 雅史/騎馬, 由佳/鈴木, 龍一郎/冨田, 夏美/上家, 明美/勇, 史行/Deng, Shixin
著者：別形式	Kitamura, Masashi / Kiba, Yuka / Suzuki, Ryuichiro / Tomida, Natsumi / Uwaya, Akemi / Isami, Fumiyuki / Deng, Shixin
著者：カナ	キタムラ, マサシ/キバ, ユカ/スズキ, リュウイチロウ/トミダ, ナツミ/ウワヤ, アケミ/イサミ, フミユキ/シシン, デン
著者：所属	城西大学薬学部 / 城西大学薬学部 / 城西大学薬学部 / モリンダワールドワイドインク / モリンダワールドワイドインク / モリンダワールドワイドインク / モリンダインク
著者：所属(別形式）	Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, School of Pharmacy, Laboratory of Pharmacognocy / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, School of Pharmacy, Laboratory of Pharmacognocy / Josai University, Faculty of Pharmacy and Pharmaceutical Sciences, School of Pharmacy, Laboratory of Pharmacognocy / Morinda Worldwide, Inc., Research and Development / Morinda Worldwide, Inc., Research and Development / Morinda Worldwide, Inc., Research and Development / Morinda Inc., Research and Development
著者版フラグ	publisher
出版地	Basel
出版者	MDPI
電子ISSN	23056320
掲載誌名	Medicines
巻	7
号	9
刊行年月	2020-09
開始ページ	1
終了ページ	6
コンテンツ作成日	2020-07-28
コンテンツ修正日	2020-09-04
コンテンツ登録日	2020-10-30
識別番号：DOI	info:doi/10.3390/medicines7090057
識別番号：DOI（リンク）	https://doi.org/10.3390/medicines7090057
抄録	Background: Hemp (Cannabis sativa L.) seed contains high contents of various nutrients, including fatty acids and proteins. Cannabidiol (CBD) is a non-psychoactive compound that can be extracted from C. sativa and used for treating epilepsy and pain. Industrial hemp products, including CBD and hemp seed oils, have become increasingly popular. Some products are marketed without a clear distinction between CBD and hemp seed oils. Herein, the CBD content and biological activities of commercial CBD and hemp seed oils were examined. Methods: CBD content was measured by high-performance liquid chromatography. For in vitro antioxidant activity determination, 2,2-diphenyl-1-picrylhydrazyl and 2,2′-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) radical-scavenging assays were performed. Results: The CBD concentrations in the two CBD oil samples were 18.9 ± 0.5 and 9.2 ± 0.4 mg/mL. Of the seven hemp seed oil samples, six samples contained CBD in concentrations ranging from 2.0 ± 0.1 to 20.5 ± 0.5 µg/mL, but it was not detected in one sample. Antioxidant activity was observed in both CBD oil samples. Conclusions: The results indicate that (1) CBD content varied by hemp seed oil sample and that (2) antioxidant activity could be a useful landmark for discriminating CBD oils from hemp seed oils.
キーワード	Cannabidiol/hemp/antioxidant/Cannabis sativa
注記	Article No.57. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
言語	eng
資源タイプ	text
ジャンル	01学術雑誌論文 / Journal Article
フォーマット	application/pdf
権利	Copyright © 2020 by the authors.
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このアイテムを表示する：URI	https://libir.josai.ac.jp/il/meta_pub/G0000284repository_JOS-medicines7090057

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